I'm honestly a little confused on what the point of this is? Of course MD is typically preferred to DO, but its rather strange you're asking us what you should do when this is clearly a choice that you and your wife need to decide on.
In your situation the others here are flat out wrong to just come out and say go MD no questions asked. The harsh reality everyone needs to face is that both MD and DO will give you the opportunity to become a doctor. You are the master of your own fate in school, you have the ability to pursue specialties of your choice, and its all about how much work you put into it.
You though do not live in a bubble I assume, your wife has her own goals and desires in life and she clearly needs to have a say in where your family goes. She clearly does not want to go to Michigan, she has a career there that will provide you security while you're in school, you have a strong support network there, you have kids. Do you think its alright to just completely upend everyone else's life just because you and only you want to move to Michigan? You need to find what works best for both of you or you will have more to worry about than just what school to go to.