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OChem: NaBH4 Reduction

Discussion in 'DAT Discussions' started by KyoPhan, Jul 25, 2011.

  1. KyoPhan

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    I just noticed that NaBH4 can't reduce a lot of stuff.
    So far, I found that they can't reduce acids/esters/NO2/alkenes

    Can they only reduce ketones and aldehydes?

    Are there any other compounds that are selective in their reduction/oxidation that I should take note of?
     
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  3. wired202808

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    hey kyo! its my turn to help u out! :laugh: NaBH4 is weak and can only reduce aldehydes, ketones and acid halides

    Meanwhile LiAlH4 can reduces ketones, aldehydes, acid chlorides, esters, carboxylic acids, and amides. (+ a few more things i might have missed)

    Hope this helps!
     
  4. rpatel8

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    LiAlH4 can also reduce nitriles. Can't think of anything else.
     
  5. Troyvdg

    Troyvdg Dentistry not Debtistry
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    it can also reduce imines
     
  6. KyoPhan

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    Awesome. Thanks:)
     
  7. rpatel8

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    Also, remember that amides get reduced to amines.
     
  8. KyoPhan

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    I just passed through that in destroyer's road map!:thumbup:
     
  9. DrRoyal Pains

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    My motto is when in doubt for reducing, always turn to LiAlH4
     
  10. wired202808

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    i feel this is very important to remember i often see problems in destroyer + other test prep where they give you products and use the reagents and u really have to remember this stuff! so try to memorize the reductions via chad's pdfs if you have them.
     

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