1. Dismiss Notice
  2. Guest, be sure to check out How To Get Into Dental School, our free downloadable PDF with step-by-step details for dental school applicants!
    Dismiss Notice
  3. Dismiss Notice
  4. Download free Tapatalk for iPhone or Tapatalk for Android for your phone and follow the SDN forums with push notifications.
    Dismiss Notice

OChem: NaBH4 Reduction

Discussion in 'DAT Discussions' started by KyoPhan, Jul 25, 2011.

  1. KyoPhan

    7+ Year Member

    Joined:
    Jun 8, 2008
    Messages:
    331
    Likes Received:
    14
    Status:
    Pre-Dental
    I just noticed that NaBH4 can't reduce a lot of stuff.
    So far, I found that they can't reduce acids/esters/NO2/alkenes

    Can they only reduce ketones and aldehydes?

    Are there any other compounds that are selective in their reduction/oxidation that I should take note of?
     
  2. Note: SDN Members do not see this ad.

  3. wired202808

    wired202808 Membership Revoked
    Removed 5+ Year Member

    Joined:
    Aug 14, 2006
    Messages:
    2,463
    Likes Received:
    9
    hey kyo! its my turn to help u out! :laugh: NaBH4 is weak and can only reduce aldehydes, ketones and acid halides

    Meanwhile LiAlH4 can reduces ketones, aldehydes, acid chlorides, esters, carboxylic acids, and amides. (+ a few more things i might have missed)

    Hope this helps!
     
  4. rpatel8

    5+ Year Member

    Joined:
    Apr 15, 2009
    Messages:
    172
    Likes Received:
    0
    Status:
    Pre-Dental
    LiAlH4 can also reduce nitriles. Can't think of anything else.
     
  5. Troyvdg

    Troyvdg Dentistry not Debtistry
    7+ Year Member

    Joined:
    Jul 13, 2009
    Messages:
    788
    Likes Received:
    188
    Status:
    Pre-Dental
    it can also reduce imines
     
  6. KyoPhan

    7+ Year Member

    Joined:
    Jun 8, 2008
    Messages:
    331
    Likes Received:
    14
    Status:
    Pre-Dental
    Awesome. Thanks:)
     
  7. rpatel8

    5+ Year Member

    Joined:
    Apr 15, 2009
    Messages:
    172
    Likes Received:
    0
    Status:
    Pre-Dental
    Also, remember that amides get reduced to amines.
     
  8. KyoPhan

    7+ Year Member

    Joined:
    Jun 8, 2008
    Messages:
    331
    Likes Received:
    14
    Status:
    Pre-Dental
    I just passed through that in destroyer's road map!:thumbup:
     
  9. DrRoyal Pains

    7+ Year Member

    Joined:
    Jul 29, 2010
    Messages:
    839
    Likes Received:
    9
    Status:
    Dental Student
    My motto is when in doubt for reducing, always turn to LiAlH4
     
  10. wired202808

    wired202808 Membership Revoked
    Removed 5+ Year Member

    Joined:
    Aug 14, 2006
    Messages:
    2,463
    Likes Received:
    9
    i feel this is very important to remember i often see problems in destroyer + other test prep where they give you products and use the reagents and u really have to remember this stuff! so try to memorize the reductions via chad's pdfs if you have them.
     

Share This Page