My advice is not to have paperwork.
Seriously. Scan it all in - if your lab has one that can scan stacks of pages at a time, great. If not, it might even be worth investing in a low-end one that is capable of this.
I could probably fill an entire room with all the paper I've read over the last few years, yet it all easily fits on my laptops hard drive. Plus I can use that lovely feature called "Ctrl-F" that papers and filing cabinets don't have. Just make sure you have multiple backups! I have a file syncing program that keeps things stored on both my laptop and desktop in case either should die, plus I back up pretty regularly to both an external HD, and off-site web-based backup in case of something truly awful (e.g. fire).