P Paramyxovirus Full Member 7+ Year Member Joined Aug 4, 2016 Messages 58 Reaction score 21 Aug 9, 2016 #1 Members don't see this ad. Ahem, can someone kindly explain why there is right sided shift of oxygen dissociation curve in SCD? Thanks in advance!
Members don't see this ad. Ahem, can someone kindly explain why there is right sided shift of oxygen dissociation curve in SCD? Thanks in advance!
Northerncardinal Full Member 7+ Year Member Joined May 25, 2016 Messages 148 Reaction score 46 Aug 9, 2016 #2 cuz of inc 2, 3 BPG due to chronic anemia. there is compensatory inc glycolysis in RBCs cuz of hypoxia Upvote 0 Downvote
cuz of inc 2, 3 BPG due to chronic anemia. there is compensatory inc glycolysis in RBCs cuz of hypoxia
P Paramyxovirus Full Member 7+ Year Member Joined Aug 4, 2016 Messages 58 Reaction score 21 Aug 9, 2016 #3 Northerncardinal said: cuz of inc 2, 3 BPG due to chronic anemia. there is compensatory inc glycolysis in RBCs cuz of hypoxia Click to expand... Thanks! Does this right sided shift happen in all kinds of Anemias? Upvote 0 Downvote
Northerncardinal said: cuz of inc 2, 3 BPG due to chronic anemia. there is compensatory inc glycolysis in RBCs cuz of hypoxia Click to expand... Thanks! Does this right sided shift happen in all kinds of Anemias?
Northerncardinal Full Member 7+ Year Member Joined May 25, 2016 Messages 148 Reaction score 46 Aug 9, 2016 #4 yes. in chronic anemias. I remember Goljan mentions the curve doesn't shift in anemia (hez referring to acute changes i think) and uworld mentions the inc in 2,3 BPG in RBCs in chronic anemias that'd eventually shift the curve to the right. Upvote 0 Downvote
yes. in chronic anemias. I remember Goljan mentions the curve doesn't shift in anemia (hez referring to acute changes i think) and uworld mentions the inc in 2,3 BPG in RBCs in chronic anemias that'd eventually shift the curve to the right.
P Paramyxovirus Full Member 7+ Year Member Joined Aug 4, 2016 Messages 58 Reaction score 21 Aug 9, 2016 #5 Thank you very much for the clarification! 🙂 Upvote 0 Downvote