Step I p450

Started by applicant2002
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applicant2002

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is there are book/website that has a list of all the P450 inducers/inhibitors that we should know for the boards.
P.S. not one of those enormous lists that have 100+ drugs on the list 🙂
thanks a million
 
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i'm guessing you want more, but FA (2003) lists a few. That's likely to be all I can remember...

Increase P450 activity - barbiturates, phenytoin, carbamazepine, rifampin, griseofulvin, quinidine

Decrease P450 activity - cimetidine, ketoconazole, grapefruit, erythromycin, isoniazid, sulfonamides
 
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Big ones to remember:
Inducers - Barbiturates, Phenytoin, Rifampin
Inhibitors - Psych drugs and Bug Drugs

Thats just a general schema we were taught. Comes in pretty handy when all else fails. 👍
 
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