Working evenings/nights/holidays many days of the month isn’t a recipe for long-term health or happiness. It’s something that’s fun in your 20’s, I admit. But, then you get older and the excitement wears off real quickly. Also, add critically ill patients, traumas, and psychiatric patients on top of the bad hours and you have a recipe for rapid burnout.
Path ain’t easy, but it’s something you can get better and more efficient at with time, and you have pretty reasonable control of your hours. Most pathologists don’t work many holidays, and they certainly don’t work many evenings or nights.