PCOS and endmetrial adenocarcinoma

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PCOS = high androgens (hence the symptoms). High circulating androgens are converted to estrone in the periphery which causes endometrial hyperplasia over time. Also PCOS = anovulatory bleeding. If you are not ovulating, you never have progesterone to balance out your estrogen = prolonged states of estrogen stimulation without counterbalance.
 
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