pharmacokinetics/dynamics

[Fatalis]

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is first aid all we really need for these 2 sections? My school went into a lot more detail [in terms of formulas, etc].
Also under what section in uworld/rx can I find sample questions for kin/dynamics? thanks

 

[ChessMaster3000]

is first aid all we really need for these 2 sections? My school went into a lot more detail [in terms of formulas, etc].
Also under what section in uworld/rx can I find sample questions for kin/dynamics? thanks

They would be under pharmacology if anything, altho I don't recall a lot of pharmacokinetics questions. I would imagine they don't go much more in depth than that, I've seen very little thus far in rx, uw, and a couple of practice tests. In fact, I haven't seen a lot of people in post-exam reviews that mention kinetics, however, I still think it is high yield since it's quick to learn

 

[Fatalis]

sounds good.
just a quick question, anyone remember EC50 vs Kd and in what situation one is greater than the other?

 

[Miracoli]

here is a Q for your question🙂
Question to Q🙂 Welcome to miracoli's world😉
Beta adrenoceptors in the heart regulate cardiac rate and contractile strength. Several studies have indicated that about 90% of adrenoceptors in the heart are spare receptors. Which of the following statements about spare receptors is most correct?
A. Spare receptors, in the absence of drug, are sequestered in the cytoplasm
B. Spare receptors may be detected by finding that the drug-receptor interaction lasts longer than the intracellular effect
C. Spare receptors influence the maximal efficacy of the drug-receptor system
D. Spare receptors activate the effector machinery of the cell without the need for a drug
E. Spare receptors may be detected by the finding that the EC50 is smaller than the Kd for the agonist

answer is on
www .usmleforum .com/files/forum/2013/1/762597.php

 

[Fatalis]

E