1) What type of pathway are you taking to become a physician scientist, and how far along are you?
I'm a PhD-to-MD, now finishing my first year of medical school. My PhD is in pharmaceutical chemistry. Basically I did organic synthesis.
2) What general advice do you have for people who want to become physician scientists by the same route you took?
Wow, this is a really tough road to getting an MD/PhD, probably the hardest way to go about it. I'm not just saying that because it's what I did, but because you have the lowest chance of getting the MD this way. I suggest that you should not plan on going this route if you're currently in college; it's really a route meant for people who come to realize they want to go to med school after the fact. If you're in college, you'd be a lot better off applying MD/PhD or straight MD and then you can do a PhD later. You're probably also going to have to pay for your MD if you go the PhD-to-MD route.
3) What application advice would you give to people who want to follow your track?
There are two really important things that you must do if you're a PhD who wants to go to medical school.
First, you must have a very good explanation for why you cannot accomplish your career goals with just your PhD. Make sure to explain this clearly in your PS and reinforce it at your interviews. You are coming in already possessing a professional degree, and it's not cool to be thirty years old and telling the interviewer that you don't know what you want to be when you grow up. You need to have a plan that seems well-thought-out, even if you reserve the right to change your mind later.
Second, you MUST go through all of the same hoops that any other MD applicant goes through. It's essential that you have the grades and MCAT scores you need to get into med school. When I say grades, I mean undergrad grades in particular. You will NOT be given special treatment or consideration for MD applications just because you have a PhD. In addition, you must have clinically relevant shadowing and volunteering experience. If you're not already shadowing and volunteering, you should start, yesterday. Again, your PhD is basically like a nice EC. It doesn't compensate for crappy college grades or a low MCAT, and it doesn't compensate for a lack of other ECs that med schools are looking for from applicants.
Where to apply: Definitely apply to all of your state schools. I would advise getting an MSAR and looking through it for other schools that have research missions, assuming you're still interested in doing research. You may also need to retake some of your pre-reqs if you took them a long time ago. Check with every school about their requirements; they vary widely.
4) What do you wish you had done differently if you could do it all again?
If I could go back ten years ago and give my college senior self advice, I'd have told her to apply to joint MD/PhD programs. If she couldn't get into one, I'd have told her to go MD-to-PhD. Seriously, I think that PhD-to-MD should be the choice of last resort, and not something you plan to do all along.