Step I platelet aggregation question

[medicinehopeful]

hey all -
what effect does the stimulation of the alpha-2 receptor have on platelet aggregation? I've read two sources, both of which contradict each other. One says it increases platelet aggregation, while the other says it decreases platelet aggregation. Thanks.

 

[Buckeye(OH)]

I just did a quick search. It would appear we don't know because the two very first hits I got on google were contradictory.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1133440

vs.

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=12913400&dopt=Abstract

 

[beastmaster]

lol Buckeye, maybe a career in research isn't for you. Those are not the same entities. alpha2 is a membrane receptor, alpha2antiplasmin is a glycoprotein in plasma.

 

[Buckeye(OH)]

lol Buckeye, maybe a career in research isn't for you. Those are not the same entities. alpha2 is a membrane receptor, alpha2antiplasmin is a glycoprotein in plasma.

Yeah, I didnt really read them. I just saw a2 and got all excited.