for biochem and physio, you must master big pictures and concepts first. Then, try to understand how all the details fit into those big pictures. If you just memorize things without TRULY understanding and not knowing how to apply, you won't honor those classes. Also, try to focus on how some pathways, mechanisms or bodily functions, or lack thereof, can cause diseases etc. However, know that just learning the big pictures and important concepts won't get you above average either.