While they didn't have this question on AMCAS last year, it was asked quite frequently on secondaries. I usually tried to give myself the out that I was planning to keep an open mind in med school, but currently, I am interested in blah-blah-blah because of blah-blah-blah. I think Jamie is right on with this one -- they kind of want to see generally what areas are you attracted to right now -- academic medicine, primary care, rural or urban setting, etc. They realize this may change, but depending on your interests, there are some med schools you are more well-suited for and vice versa. My best advice is to be honest --if you aren't actually interested in primary care, don't lie and say that you are, etc.