I've noticed when I have a cold that taking pseudoephedrine (Sudafed) makes me a little wired. Don't have a cold now but the other night, working on four hours of sleep and going into another night time ED shift, I decided to take a 12-hour extended release pseudoephedrine tablet. It was great! Not only was I awake and feeling more enthusiastic than usual, I didn't need to eat or pee for almost my whole shift (definitely an advantage when you're running from patient to patient). So my question obviously is: is it dangerous to take a little pseudoephedrine once in awhile for this reason? If I were to do it during my surgery rotation or during residency when I'm on call, say once or twice a week, would I be running the risk of addiction or other problems? Anybody else tried this?