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When comparing W2/1099 positions, to compare apples to apples you factor in the differences in the extra taxes you are paying as a 1099 and the lack of benefits.
for instance, assuming a 250k salary - you are paying an extra $3625 in Medicare (1.45% of 250k) and $7347 in Social Security tax (6.2% of 118,500) for a total of $10,972 extra as a 1099 compared to W2
then, you have to add the extra expenses of Health insurance, malpractice, and retirement.
Those last 3 factors are variable depending on your personal health/#of people covered in your family (health insurance premiums), # of years you've been practicing (malpractice premiums), and whether the W2 position provides a match (e.g. 6% match versus no match). As a 1099, keep in mind that you can put away up to 53k as backdoor roth, which you don't pay tax on when you retire.
Or.... you can be savvy enough to find a position that pays you on W2 where you can get Benefits. Let's face it, the demand side allows for plenty of negotiating how you can derive revenue.
Conceptually when planning employment, don't think of work as an "all 1099" or "all W2". Mix and match the opportunities to fit your needs and make the most with the least amount of hours. And don't forget to find employment which nurtures and challenges you, and allows you to be you.