Aug 16, 2015
13
1
Status
Pre-Medical
I think I am overthinking this but I am very confused why you would have increased parathyroid hormone levels with rickets.
Because rickets has decreased vitamin D and I know that PTH increased calcium when it is low so i understand that, but because it increased calcium levels, why would there be low vitamin D still because PTH is supposed to increase calcium???
 

Neuroplasticity

2+ Year Member
Jul 27, 2015
102
53
Status
Medical Student (Accepted)
I think you may be thinking about cause and effect of rickets the wrong way around. Low vitamin D causes rickets, rickets does not cause low vitamin D. So having rickets means you have low vitamin D.
Vitamin D increases intestine Ca2+ absorption, so when you have low vitamin D, you have less intestine Ca2+ absorption which leads to low blood Ca2+. To raise blood Ca2+, you increase parathyroid hormone levels.