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I go to Duke, and we're required to do a year of research during our third year. I'm interested in ophthalmology and would like to do ophtho research. If I stayed at Duke, I'd probably be able to get a LOR from both my research adviser and the head of the ophtho dept, who apparently gets to know all the student researchers pretty well. However, I'm not really a fan of Durham and would prefer to go elsewhere for the year (I'm thinking of applying for a Doris Duke Fellowship or trying to go to the NIH). My question is - would I be dumb to give up those 2 letters from Duke, which has a good reputation in ophtho, to go somewhere that might not have as good of a reputation? How important are the connections you make when applying to residency? Thanks.