do they fill better or worse with increased diastolic pressure? thanks! p.s. i'm just kind of confused from Goljan's explanation about all the stuff that happens after you have a decreased cardiac output. He says the arterioles constrict because of catechols, resulting in maintenance of diastolic pressure. But that it's good news for the coronaries b/c they get filled then. I know that's when they get filled, but wouldn't they also constrict from the alpha1 effect? good luck to all who are taking it soon!