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So I have couple of things that I am not sure if I have it straight.
1) So when we are talking about Hypo/hyperkalemia, we are talking about K+ concentration in serum and NOT inside cells. Am I right?
2) Lasix (loop diuretic) causes Metabolic Alkalosis. It does so by preventing K+ reabsorption (blocks NKCC) so serum K+ decreases. This causes a transcellular shift which causes K+ to leave the cell and go into serum and H+ from serum going into cell. Low serum H+ causes Alkalosis. Am I right?
3) Hyperkalemia is associated with metabolic acidosis. Same principle. High K+ in serum would go into the cell which would causes H+ in the cell to come out into the serum causing acidosis?
I just need to know if thats what exactly happening? I get confused by this quite often. Thanks
1) So when we are talking about Hypo/hyperkalemia, we are talking about K+ concentration in serum and NOT inside cells. Am I right?
2) Lasix (loop diuretic) causes Metabolic Alkalosis. It does so by preventing K+ reabsorption (blocks NKCC) so serum K+ decreases. This causes a transcellular shift which causes K+ to leave the cell and go into serum and H+ from serum going into cell. Low serum H+ causes Alkalosis. Am I right?
3) Hyperkalemia is associated with metabolic acidosis. Same principle. High K+ in serum would go into the cell which would causes H+ in the cell to come out into the serum causing acidosis?
I just need to know if thats what exactly happening? I get confused by this quite often. Thanks