This thread got necrobumped at a good time, and as someone who had no idea what taxes would be like as a med student I want to give back in this domain. I printed my tax forms today so here is my real, unadultered data. I do max out my 401k and HSA.
Regular pay - $349,950
Taxes (state, federal, local, FICA, Medicare) - $138,650
Insurance, diabilitiy, medical, vision, dental, HSA, 401k- $30,500
Parking - $450
Net pay: $180,800 giving me a net pay of 52% of my gross.
Note - as mentioned, W2 does have its perks. My company paid out $56,000 in taxes, benefits and matching on my behalf, giving me an effective 1099 salary of ~$405,000.