So, I've been away form college for a year and want to use a PI in lieu of a science professor--no biggie right? I've also only taken "Honors Molecular & Cell bio" which was a semester with lab. So, technically my requirements for bio aren't completed. I did take a bio chem class w/o lab, mammilian physiology w/o lab, and human anatomy, for which I took lab, then taught lab. So I can't see either of these being much of a problem. On to the question: when should I e-mail about this? Don't schools wait till acceptances to check if your requirements suffice (e.g. they as for your transcripts)? And for the LORs, if I emailed them would they just place a "stick-it note" on my application that says "this guy called and asked if he could do this, so it's OK." I figure I should e-mail about the LOR now, but am not sure on when I should ask about waiving the bio requirement, for fear of raising flags early on (paranoid? maybe) Any experiences (preffered) or speculation? thanks, OM.