I think it really depends on the rest of your application. If your GPA is suppose to be one of the strong suits of your application then retake those Cs! But if your PCAT, pharmacy experience and extra currics are strong then it may not be a big deal depending on where you apply.
If you want to be safe I would get rid of the Cs on your application, I say this because my pharmacy advisor told me the summer before I apply I really should get rid of my C in physics and statistics if I wanted a a better shot at getting in. This is because my GPA is very average, 3.4, if I had a higher GPA then I could have gotten away with a couple Cs but with a mediocre GPA you reaLly have to retake.