Site of transcription and translation?

[Longcatislong]

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Can someone clarify this for me. I've got two sources that say different things.

DNA replication occurs in the nucleus
Transcription occurs in the nucleus
translation occurs in the cytoplasm or the nucleolus??

 

[free99]

Translation occurs in the ribosomes on the rough ER in the cytoplasm.

 

[FeralisExtremum]

Translation occurs in the cytoplasm, not the nucleolus.

The confusion may be because the nucleolus is the site of rRNA synthesis (along with ribosome subunit assembly).

 

[Longcatislong]

Thank you!

 

[IsaacYankem]

Also, remember that eukaryotes have the spatial segregation of transcription (nucleus) and translation (cytoplasm). Hence why eukaryotes have the 5' GTP cap and 3' poly A tail to help guide mRNA through nucleus--> cytoplasm

Prokaryotes don't have membrane bound organelles, so there is no segregation of these processes and can be done simultaneously. As soon as the mRNA is transcribed, prokaryotes can translate it immediately.

 

[FeralisExtremum]

As soon as the mRNA is transcribed, prokaryotes can translate it immediately.

Transcription and translation can even occur simultaneously, if I'm not mistaken.

 

[Bis-GMA111]

Transcription and translation can even occur simultaneously, if I'm not mistaken.

in prokaryotes yup. not in eukaryotes

 

[free99]

Also, remember that eukaryotes have the spatial segregation of transcription (nucleus) and translation (cytoplasm). Hence why eukaryotes have the 5' GTP cap and 3' poly A tail to help guide mRNA through nucleus--> cytoplasm

Prokaryotes don't have membrane bound organelles, so there is no segregation of these processes and can be done simultaneously. As soon as the mRNA is transcribed, prokaryotes can translate it immediately.

👍 No introns in prokaryotic DNA as well (ie, the entire genome is coding)