It seems like both SLE and RA pretty much can have the same manifestations. Both are autoimmune and can target the same organ systems. Is detecting anti smith and anti dsDNA, etc for SLE the only way to differentiate the two?
Look for the SLE associated rashes (discoid, malar, photosensitivity). Also non-deforming joint pain.
RA is more joints and kidney, whereas SLE is likely to involve everything.
Thats probably true. I'm just fresh off a Uworld, Amyloidosis/RA question so thats probably why.heart, eyes, and lungs before kidney in RA. I don't remember CKD being a big part of RA, whereas SLE glomerulonephritis is definitely huge
Thats probably true. I'm just fresh off a Uworld, Amyloidosis/RA question so thats probably why.
I didn't expect Felty's to show up, but I ran into it on an NBME I took the other day.yeah you're absolutely right but the others are more common. I had to look it up, amyloidosis is one of the most common systemic causes of the nephrotic syndrome but it's only clinically relevant in 1-2% of RA patients. Which means it's still more common than Felty's, which is definitely rare but for some reason that's the one everyone remembers. The one I always think of anyway