Steroid hormone and nuclear receptors

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ChessMaster3000

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I read sometimes that steroid hormones (as in glucocorticoids) have cytoplasmic receptors and sometimes have nuclear receptors. ON another thread in this forum from a long time ago, someone wrote that steroid hormones don't need cytoplasmic receptors--what does that mean? How do you know when/if a steroid hormone needs a cytoplasmic receptors and when it doesn't? For the records, I understand that thyroid hormone, Vitamin A, and Vitamin D rely on nuclear receptors.

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I think this is just something you have to memorize? Some of the steroid hormone receptors are in the cytoplasm, some are already in the nucleus.

FC says this

  • Cytosolic: Vitamin D, Estrogen, Testosterone, Cortisol, Aldosterone, Progesterone. Remember VET CAP

  • Nuclear: T3/T4

I guess they don't think VitA, K, or E are important.

Edit: Just realized you weren't asking what I answered. My bad.
 
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