Strecker and Gabriel Synthesis

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DPTinthemaking15

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I have searched a few threads and I cannot find the answer I am looking for. What is the takeaway point when I look at these mechanisms? My Professor never covered these topics in class, and I am not sure what I should really understand when I go through them.
 
Hi @DPTinthemaking15 -

A relatively small investment of time should allow you to recognize, in rough order of importance: (1) their outputs, (2) their inputs, and (3) differences between them that would allow you to tell them apart. I would definitely recommend that level of knowledge—i.e. basic recognition—as a minimum. This basic minimum may allow you to answer some simpler questions on it, and will at least give you a starting point for more detailed questions.

A larger amount of time investment would be to work through each step with the goal of being able to give a one-sentence explanation of what is happening and why. The takeaway should not be that you memorize the resulting script, but that you grind through it a couple times so that if it comes up on Test Day and you get a question involving some intermediate step, you will have thought about it before so hopefully it will come back somewhat effectively. Much more detail than that, IMO, would fall into the category of things to worry about if you are running out of other things to study. Certainly focus on major steps, not on fiddly details like successive rounds of protonation/H2O addition in the second stage of the Strecker synthesis.

Hope this helps provide some clarity!!
 
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