Surgical Site Infection Management

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drrinoo

Rinoo Shah, MD
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Just curious how folks are managing their implant infections:

I typically remove all the hardware, wide debridement of necrotic tissue, irrigation, and then I place a VAC pack...multiple cultures/tissue swabs....perioperative antibiotics and then change once cultures come back...

I typically work with a physiatry colleague who specializes in wound care and he uses an interesting cocktail of topicals, which sometimes includes bacteriophages!

The wounds heal well.

However, I have seen one neurosurgical colleague use delayed primary closure.

Which method do you all like to use?
Has anyone salvaged the leads, in a situation where the battery was infected?

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I agree with the removal of all hardware. I am currently finishing fellowship and plan to deal with my infected devices that we. At CC we see quite a few infected stimulators and occasionally pumps. Dr. Stanton Hicks said to a collegue of mine today that he believes 80% of infected devices can be salvaged(if only generator involved). This may be anecdotal but the man has balls of steel. I have seen in 10 months maybe 5 or 6 cases where he leaves the leads in and just removes the battery. He waits 4 months then places the battery on the other side. On two occasions he's had patients with more than 1 generator and he removed one system and left the other with no probs. And get this, he had a patient with 3 stimulator generators, took one out for infection, had it heal with a vac dressing for a month, then the second generator got infected, took it out and left the third one in! Of course this is in a big institution and he is insulated from lawsuits and the endless phone calls that his RSD patients make.
Most attendings here close the wound unless they feel it is too purulent and can't clean it, but this may not be the best answer either because I have seen several wounds dehisce.


drrinoo said:
Just curious how folks are managing their implant infections:

I typically remove all the hardware, wide debridement of necrotic tissue, irrigation, and then I place a VAC pack...multiple cultures/tissue swabs....perioperative antibiotics and then change once cultures come back...

I typically work with a physiatry colleague who specializes in wound care and he uses an interesting cocktail of topicals, which sometimes includes bacteriophages!

The wounds heal well.

However, I have seen one neurosurgical colleague use delayed primary closure.

Which method do you all like to use?
Has anyone salvaged the leads, in a situation where the battery was infected?
 
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This is one of most influential pain physicians alive you are talking about. He has put in 2-4 stim implants a weeks since the early 90's. I think he knows a little more about pain and stims than you or definetly I do.
As far as patient follow up, he brings the patients back regularly and tells them what signs and symptoms to watch out for. In actuality, is it right or wrong to do this? I think it depends on your relationship with the patient and the patient him/herself. Don't get me wrong, I would likely take the things out, but the question is, does the whole thing need to come out? Sounds like he should put together a retrospective review...
 
Thanks for your reply.

In the patient with the three batteries...did the second surgical site infection grow out the same bug as the principal surgical site infection?

If this is the case, it interesting that the PNS/SCS leads did not get infected.

Also, for the cases where you salvage the leads, do you obtain tagged wbc scans to exclude a lead infection?
 
We usually explant the system at this time, but partially this depends on whether the infection is in the pocket or is a superficial infection above the pocket. If it is above the pocket, we retain the system. In the past, before the document by Folett was published, we would actually salvage the pumps and stims by a thorough soak in bacitracin solution during the time we were irrigating the wound with 3 liters of irrigant. In that way we were able to salvage about 1/2 the pumps and stims that otherwise would have been explanted, and there is a more recent paper that suggests that is possible based on a small series. But the hospital infection control committees believe strongly that the hardware should be entirely explanted even if it means a return to severe intractable pain that in one of my patients lead to a suicide attempt. But the infection control committees have covered their rear ends and feel no culpability for patients that will never get another pump or stim because some of these patients are on Medicaid, that does not pay for these devices in our state.
Recently, I treated a patient for what I thought was infection due to erythema of the skin directly over the pump, and the diabetes was much more difficult to control. I made the decision to operate and culture, with probable explant. There was no purulence and in fact no drainage at all when the wound was opened, gram stain was negative, and subsequently only s. epidermidis was cultured. The cause of the erythema was the patient's massive intraabdominal fat content causing compression of the pump against the skin due to the fact that he had virtually no fat between the external abdominal oblique and the skin. The pump was revised to another pocket, remained without infection, but the internists on the infection control committee went ballistic anyway, claiming the entire system should have been removed for a s. epi culture. Is that your understanding- that skin organism cultures should result in explantation of a pump or stim when there is no drainage, a negative gram stain, no fluid in the pocket, no fever?
 
algosdoc said:
We usually explant the system at this time, but partially this depends on whether the infection is in the pocket or is a superficial infection above the pocket. If it is above the pocket, we retain the system. In the past, before the document by Folett was published, we would actually salvage the pumps and stims by a thorough soak in bacitracin solution during the time we were irrigating the wound with 3 liters of irrigant. In that way we were able to salvage about 1/2 the pumps and stims that otherwise would have been explanted, and there is a more recent paper that suggests that is possible based on a small series. But the hospital infection control committees believe strongly that the hardware should be entirely explanted even if it means a return to severe intractable pain that in one of my patients lead to a suicide attempt. But the infection control committees have covered their rear ends and feel no culpability for patients that will never get another pump or stim because some of these patients are on Medicaid, that does not pay for these devices in our state.
Recently, I treated a patient for what I thought was infection due to erythema of the skin directly over the pump, and the diabetes was much more difficult to control. I made the decision to operate and culture, with probable explant. There was no purulence and in fact no drainage at all when the wound was opened, gram stain was negative, and subsequently only s. epidermidis was cultured. The cause of the erythema was the patient's massive intraabdominal fat content causing compression of the pump against the skin due to the fact that he had virtually no fat between the external abdominal oblique and the skin. The pump was revised to another pocket, remained without infection, but the internists on the infection control committee went ballistic anyway, claiming the entire system should have been removed for a s. epi culture. Is that your understanding- that skin organism cultures should result in explantation of a pump or stim when there is no drainage, a negative gram stain, no fluid in the pocket, no fever?

Algos,

You pose a very difficult problem, but your decision making process is perfectly logical. Assume your child has a self limited URI and recovers completely. If Strept cultures come back positive a few days later and the pediatrician prescribes Abx...do you give it? Similar dilemma.

I think I would have done something similar, if it were a baclofen pump. ITB withdrawal is life threatening. I would probably breakdown and use a new pump however...I would be nervous about a residual infectious biofilm on the old pump ....Your bacitracin soaking idea is great; it probably kills all the bacteria....but, I am also concerned about not completely disrupting the biofilm scaffolding.

I would probably do something along the lines of...open the posterior midline incision....identify the catheter and cut it proximal to the anchor... and tie it off ....(after induction of GETA, I may program the pump to give a low dose ITB bolus over 20 minutes)...then go to the ant. abdominal wound and release the pump and pull out the proximal catheter. Pack the ab wound with a VAC pack and tegaderm/ioband the midline incision...flip the patient....new equipment/new prep...and get a new IT pump and use a 2 piece catheter system to reconnect....I may get CSF culture from the catheter as well.


If it were a regular IT pump with opioids....I would probably explant the system, but program a bolus equivalent to 25% of the daily dose, prior to removal...if the infection is more subtle, then I would wean the pump drug dose.....then I would come back and replace it a few months later.

In any case, the decision to explant or leave it in is a very tough one...

It would be great to publish your case as a case report...it is very admirable that you did your best to help your patient.

Finally, why did your case go to a hospital committee, if it wasn't Meth Resistant SE? Ordinarily, you just consult the ID specialist and they render an opinion.

Were the committee's decisions protected as confidential peer review, primarily for education purposes, e.g. like an M+M conference...or was there another agenda? For instance, did they solicit the opinions of other surgeons in the hospital, just to give you a hard time--I am asking you to read between the lines, before you answer.
 
lol...I wish it were simply for education purposes. I think I must have pissed someone off on the credentials committee or they were influenced by an ex-partner on the executive committee....go figure. Not all medicine lies in the realm of science: there are politics that vex us in practice, and these are sometimes more difficult to figure out than patient care issues....
 
algosdoc said:
lol...I wish it were simply for education purposes. I think I must have pissed someone off on the credentials committee or they were influenced by an ex-partner on the executive committee....go figure. Not all medicine lies in the realm of science: there are politics that vex us in practice, and these are sometimes more difficult to figure out than patient care issues....


These points are more valid than the actual infection in the patient. THe body is remarkable in its ability to handle everything that is thrown at it. I've seen pus filled pockets treated with Cipro for 14 days completely resolve. I've seen mild superficial skin infections turn into MRSA requiring 6 weeks ABX.

THe medicolegal and political side often influences care to be overly protective as we cannot just see how things play out. It is not worth the risk. Cellulitis gets ABX, deeper infections get ABX and explanted. I'm no hero and want to be doing this for 20 more years.
 
I leave an infected pocket open and pack it, then send them home with home health f/u for wound care.

There are some pocket infections that seem to fester before declaring themselves. There is erythema, and the aspirate will have a lot of polys but no bugs. A week or two after that presentation they turn to frank pus. I have injected those pockets with vancomycin in the early stages and I think I have headed off some explantations.

The ID guy brought up the possibility of sterile abscesses with vanco in the pocket. I told him it's better to have a sterile abscess than the other kind. ;)

Prophylaxis:

1. Phisohex shower for three days before procedure.

2. Vanco 1 - 1.5 gm IV prior to incision.
 
I spoke with a local ID colleague. In his experience, the infection control committee has never acted as a proxy for the credentials committee.

Nonetheless, several colleagues of mine have said that the infection control committees do report to higher level committees.

Now that hospitals have to publicly disclose certain performance/outcome measures...such as infection rates, we may begin to witness more of what Algos had to go through.

Dr. Gorback,

The phisohex idea is a good one....I'll have to consider it. The stratum corneum has a lot of oil and I'm not sure if the betadine/duraprep saponify the oils.

Another tip....let the nurse clean the patient and don't rush him/her....don't let a physician prep.
 
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