Ok, totally lost, when do you use normal saline, D5W, 0.45% saline? So, according to UW, use normal saline for sever hypernatremia, initial resusc. in DKA, etc, then you can switch D5W. Kaplan Qbank, got a Q, pt has Na 163, what do you - D5W, reason ? - need to give hypotonic solution to correct the hypernatremia. Wait - if you give hypotonic solution in severe hypernatremia, there is a risk for cerebral edema and seizures. So, how do you treat hypernatremia ?😕😕: