- Joined
- Nov 6, 2015
- Messages
- 3,086
- Reaction score
- 6,300
Cool case to share from the other day:
ED Case:
28yo F presents to the ED for 2 weeks of malaise, subjective fevers at home, chills, scant vaginal bleeding, chest pain, RUQ & RLQ abd pain, and palpitations. Arrived here from Guatemala 2 weeks ago, denies PMH/PSH/meds/allergies.
Triage vitals HR130, BP 91/45, O2 100, Temp 37.1, RR 16.
Got fentanyl and IVF 1L.
POC preg faintly positive.
US - no baby, ball looking thing in uterine wall, not sure what it is, FAST negative, IVC plethoric, RV strain with bowing of the cardiac septum.
Send labs, Trop in 0.2 (normal 0.034), BNP 2000, HCG 150 (so barely positive by our assay), WBC 13, AST/ALT 500s, elevated alk phos, normal Tbili. Hb 13. Urine is bloody, not infected. Lactic 1.3.
EKG is just sinus tachycardia wo RV strain pattern or stemi.
No idea wtf is going on - so decide risks outweigh benefits, CTA for PE and CT Abd with IV contrast - all completely negative. Again they see this ball thing in the uterus - they call it as likely a fibroid. So we get a transvaginal US, which is read as normal, but again they note an “intraluminal uterine fibroid, attention on followup”.
She responds well to IVF, gets a 2nd L and BP increases to 110/55.
Pelvic exam shows scant blood without discharge, fetal parts/tissue, or hemorrhage. Normal cervix.
We call OBGYN - not sure what’s going on but maybe it’s an ectopic somewhere? Is the ball really a fibroid? OBGYN resident signs off, says repeat bHCG in 48 hours, the ball is probably a fibroid, and the beta is likely from a completed spontaneous AB - possibly due to structural issues from fibroid.
Pt spikes fever to 38.5. At this point we surrender, cover with vanc and Cefepime, admit to medicine for septic workup without a source.
Inpatient course:
Blood cultures come back 2/2 positive for EColi. Super weird.
Formal echo shows mild RV strain, trended trops remain stable and modestly elevated at 0.2. Cards says likely a stress cardiomyopathy from sepsis, maybe with so pre-existing pulmonary HTN. No evidence of endocarditis or valve pathology. Nothing to do on their end.
Given the elevated transaminases surgery is consulted, they get a Hida scan, and it’s negative for biliary pathology. They sign off.
HCG at 48 hours is unchanged, still low 100s.
Repeat echo at 48 hours shows worsening global myocardial dysfunction. She’s still spiking fevers.
I’m curious and still following along, so at this point I decided to ask my wife - who’s the senior resident covering nights on GYN to look over her chart and see if there’s anything the other Day gyn resident missed.
Wife reads the TVUS and says that’s not a fibroid, that looks like retained products of conception. She goes at 3am to talk to the patient when her family is not there. The patient confesses to her that she actually had a surgical termination of pregnancy done in Guatemala 2 weeks ago immediately before coming to the US, but didn’t want her family to know so she didn’t tell anyone.
Wife gets a stat pelvis MRI at 3am (fancy toys at the womens hospital), they confirm a “loculated retained POC w/ signs of infection - most consistent with a septic abortion”. GYN team is with her in the OR now doing a formal dilation and evacuation.
So moral of the story, septic AB with stress cardiomyopathy from sepsis in a 28 year old.
ED Case:
28yo F presents to the ED for 2 weeks of malaise, subjective fevers at home, chills, scant vaginal bleeding, chest pain, RUQ & RLQ abd pain, and palpitations. Arrived here from Guatemala 2 weeks ago, denies PMH/PSH/meds/allergies.
Triage vitals HR130, BP 91/45, O2 100, Temp 37.1, RR 16.
Got fentanyl and IVF 1L.
POC preg faintly positive.
US - no baby, ball looking thing in uterine wall, not sure what it is, FAST negative, IVC plethoric, RV strain with bowing of the cardiac septum.
Send labs, Trop in 0.2 (normal 0.034), BNP 2000, HCG 150 (so barely positive by our assay), WBC 13, AST/ALT 500s, elevated alk phos, normal Tbili. Hb 13. Urine is bloody, not infected. Lactic 1.3.
EKG is just sinus tachycardia wo RV strain pattern or stemi.
No idea wtf is going on - so decide risks outweigh benefits, CTA for PE and CT Abd with IV contrast - all completely negative. Again they see this ball thing in the uterus - they call it as likely a fibroid. So we get a transvaginal US, which is read as normal, but again they note an “intraluminal uterine fibroid, attention on followup”.
She responds well to IVF, gets a 2nd L and BP increases to 110/55.
Pelvic exam shows scant blood without discharge, fetal parts/tissue, or hemorrhage. Normal cervix.
We call OBGYN - not sure what’s going on but maybe it’s an ectopic somewhere? Is the ball really a fibroid? OBGYN resident signs off, says repeat bHCG in 48 hours, the ball is probably a fibroid, and the beta is likely from a completed spontaneous AB - possibly due to structural issues from fibroid.
Pt spikes fever to 38.5. At this point we surrender, cover with vanc and Cefepime, admit to medicine for septic workup without a source.
Inpatient course:
Blood cultures come back 2/2 positive for EColi. Super weird.
Formal echo shows mild RV strain, trended trops remain stable and modestly elevated at 0.2. Cards says likely a stress cardiomyopathy from sepsis, maybe with so pre-existing pulmonary HTN. No evidence of endocarditis or valve pathology. Nothing to do on their end.
Given the elevated transaminases surgery is consulted, they get a Hida scan, and it’s negative for biliary pathology. They sign off.
HCG at 48 hours is unchanged, still low 100s.
Repeat echo at 48 hours shows worsening global myocardial dysfunction. She’s still spiking fevers.
I’m curious and still following along, so at this point I decided to ask my wife - who’s the senior resident covering nights on GYN to look over her chart and see if there’s anything the other Day gyn resident missed.
Wife reads the TVUS and says that’s not a fibroid, that looks like retained products of conception. She goes at 3am to talk to the patient when her family is not there. The patient confesses to her that she actually had a surgical termination of pregnancy done in Guatemala 2 weeks ago immediately before coming to the US, but didn’t want her family to know so she didn’t tell anyone.
Wife gets a stat pelvis MRI at 3am (fancy toys at the womens hospital), they confirm a “loculated retained POC w/ signs of infection - most consistent with a septic abortion”. GYN team is with her in the OR now doing a formal dilation and evacuation.
So moral of the story, septic AB with stress cardiomyopathy from sepsis in a 28 year old.