Thoughts on Nucynta.

This forum made possible through the generous support of SDN members, donors, and sponsors. Thank you.
The first thing I thought was that it was prolly cheaper to just give them a generic effexor and MSIR....

...but it's too new and generally unused for me to actually know much about it practically...
 
Farmercyst said:
Our pain mgmt guys are starting to write for it quite frequently. I haven't had that class yet, but it sounds intriguing if not promising.
Click to expand...

I have not looked at this in depth yet, but when I originally saw the FDA press release, I questioned how in the world this was different than tramadol......you can tell me what you think (you are intrigued), but I will eventually read for myself and tell everyone how it is.
 
Seizure warning, serotonin syndrome warning, contraindicated with MAO inhibitors, yeah, sounds the same to me...
 
Priapism321 said:
Seizure warning, serotonin syndrome warning, contraindicated with MAO inhibitors, yeah, sounds the same to me...
Click to expand...

So it's more like taking tramadol and like a .3mg of Buprenex at the same time?

We need some heroin addicts up in this to tell us what's up. We need comparative trials.
 
Yeah, I looked at the thread in Pain Rounds and I'm less intrigued, but I'll probably still look into it and see what I can glean based on how little I know so far.
 
Wow...and there we go. A thread on one of the druggie forums about Nucynta.

I'm tellin' ya...this stuff is great, great investigative stuff. It's been almost centuries since we've been able to perform unethical and dangerous experimentation on humans...yet here we have thousands doing it voluntarily. These sites are a gold mine of scientific inquiry.
 
WVUPharm2007 said:
Wow...and there we go. A thread on one of the druggie forums about Nucynta.

I'm tellin' ya...this stuff is great, great investigative stuff. It's been almost centuries since we've been able to perform unethical and dangerous experimentation on humans...yet here we have thousands doing it voluntarily. These sites are a gold mine of scientific inquiry.
Click to expand...
Holy crap, it's like a parallel dimension of SDN-- the junkie version. @_@
 
WVUPharm2007 said:
Wow...and there we go. A thread on one of the druggie forums about Nucynta.

I'm tellin' ya...this stuff is great, great investigative stuff. It's been almost centuries since we've been able to perform unethical and dangerous experimentation on humans...yet here we have thousands doing it voluntarily. These sites are a gold mine of scientific inquiry.
Click to expand...


Try this one:

http://www.bluelight.ru/vb/showthread.php?t=347068

They were talking it up since 2007!!!

google any drug name add the word bluelight...thses guys seem a little hardcore...def not the average addict...prolly some doper RPh's
 
Look ma, it's Tramadol in sheep's clothing......
 
Priapism321 said:
Seizure warning, serotonin syndrome warning, contraindicated with MAO inhibitors, yeah, sounds the same to me...
Click to expand...
-- These warnings are class warnings and were not seen in the clinicals for Nucynta (of over 3000 patients).
 
caringperson2 said:
-- These warnings are class warnings and were not seen in the clinicals for Nucynta (of over 3000 patients).
Click to expand...

Class warnings mean we are not dealing with a novel drug, so my argument holds. When I write for an opioid/catecholamine agent, it is generic tramadol. That is it.
 
Old Timer said:
Ryzolt, Ultram whatever....... Please tell me there is a difference......
Click to expand...
UltramER (which has been on the market for 3+yrs) has a different delivery system (for chronic pain) than Ryzolt (which just entered the market this yr). UltramEr delivers the total drug over 24hrs. Ryzolt gives a 50mg spike initially and then the remaining drug over 24hrs. So apples to apples, the Ryzolt patient may have less drug on board toward the end of the 24hrs than then UltramER patient. This drug is a chronic med so why the need to spike the drug ?
 
metrarx said:
Hot digitty! You write for opioid agents?

Have you ever written yourself a script? Hmmm?

Nah, you're to uptight:meanie:
Click to expand...

I write for whatever I want.....legally.
 
You know, in a "quasi-prescribing, bitch-work" kind of way.....
 
WVUPharm2007 said:
That before the physicians throw quarters at your feet and say "Dance, underling!"
Click to expand...

I am a horrible dancer. Questions and quarters from physicians come very rarely in my real world.
 
caringperson2 said:
UltramER (which has been on the market for 3+yrs) has a different delivery system (for chronic pain) than Ryzolt (which just entered the market this yr). UltramEr delivers the total drug over 24hrs. Ryzolt gives a 50mg spike initially and then the remaining drug over 24hrs. So apples to apples, the Ryzolt patient may have less drug on board toward the end of the 24hrs than then UltramER patient. This drug is a chronic med so why the need to spike the drug ?
Click to expand...


BULL****. In the real world, there are no differences....... Ryzolt is a BS meeeee tooooo drug that drives me insane.....
 
WVUPharm2007 said:
Well, I dance for quarters. I'm a ***** like that. And its a good second income.
Click to expand...

Well, I mean, I guess I would take them if they were bounced my way.....
 
caringperson2 said:
-- These warnings are class warnings and were not seen in the clinicals for Nucynta (of over 3000 patients).
Click to expand...

Drug rep much?

And now that you mention the clinical trials, the data that you guys have been handing out would not push me towards using this. If you're going to use osteoarthritis for the set of CP patients, it would help if there is a decent difference between Nucynta and placebo.
 
Last edited:
You must log in or register to reply here.

Similar threads

BC_89
Thoughts on Having Multiple Board Certifications?
Replies
31
Views
5K
WVUPharm2007
WVUPharm2007
R
Effects of tariffs on drug supply chain?
Replies
1
Views
980
lord999
lord999
M
Are pharmacists leaving $ on the table?
Replies
2
Views
2K
BenJammin
BenJammin
Mr.Smile12
[AACP] AACP Statement on NIH Facilities and Administrative Costs Impact on Colleges and Schools of Pharmacy
Replies
1
Views
757
lord999
lord999
P
The War on Stimulants
Replies
8
Views
2K
VA Hopeful Dr
VA Hopeful Dr
Top