Thoughts on Nucynta.
Started by Farmercyst
The first thing I thought was that it was prolly cheaper to just give them a generic effexor and MSIR....
...but it's too new and generally unused for me to actually know much about it practically...
...but it's too new and generally unused for me to actually know much about it practically...
I have not looked at this in depth yet, but when I originally saw the FDA press release, I questioned how in the world this was different than tramadol......you can tell me what you think (you are intrigued), but I will eventually read for myself and tell everyone how it is.
Seizure warning, serotonin syndrome warning, contraindicated with MAO inhibitors, yeah, sounds the same to me...
So it's more like taking tramadol and like a .3mg of Buprenex at the same time?
We need some heroin addicts up in this to tell us what's up. We need comparative trials.
Yeah, I looked at the thread in Pain Rounds and I'm less intrigued, but I'll probably still look into it and see what I can glean based on how little I know so far.
I like drugs-forum.com. If you want to know ANYTHING about the pharmacology, cmax, potentiation of drug effects...those people are on point...I seriously respect their scientific obsession with getting high...
Wow...and there we go. A thread on one of the druggie forums about Nucynta.
I'm tellin' ya...this stuff is great, great investigative stuff. It's been almost centuries since we've been able to perform unethical and dangerous experimentation on humans...yet here we have thousands doing it voluntarily. These sites are a gold mine of scientific inquiry.
I'm tellin' ya...this stuff is great, great investigative stuff. It's been almost centuries since we've been able to perform unethical and dangerous experimentation on humans...yet here we have thousands doing it voluntarily. These sites are a gold mine of scientific inquiry.
Ummmmmmm..............wow.
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Holy crap, it's like a parallel dimension of SDN-- the junkie version. @_@
Try this one:
http://www.bluelight.ru/vb/showthread.php?t=347068
They were talking it up since 2007!!!
google any drug name add the word bluelight...thses guys seem a little hardcore...def not the average addict...prolly some doper RPh's
Haha you mean Ryzolt, right?
Ryzolt, Ultram whatever....... Please tell me there is a difference......
The Medical Letter will be publishing an issue in mid- Aug regarding Nucynta. (Also check out www.Nucynta.com).
-- These warnings are class warnings and were not seen in the clinicals for Nucynta (of over 3000 patients).
Class warnings mean we are not dealing with a novel drug, so my argument holds. When I write for an opioid/catecholamine agent, it is generic tramadol. That is it.
UltramER (which has been on the market for 3+yrs) has a different delivery system (for chronic pain) than Ryzolt (which just entered the market this yr). UltramEr delivers the total drug over 24hrs. Ryzolt gives a 50mg spike initially and then the remaining drug over 24hrs. So apples to apples, the Ryzolt patient may have less drug on board toward the end of the 24hrs than then UltramER patient. This drug is a chronic med so why the need to spike the drug ?
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Hot digitty! You write for opioid agents?
Have you ever written yourself a script? Hmmm?
Nah, you're to uptight
I write for whatever I want.....legally.
You know, in a "quasi-prescribing, bitch-work" kind of way.....
That before the physicians throw quarters at your feet and say "Dance, underling!"
I am a horrible dancer. Questions and quarters from physicians come very rarely in my real world.
BULL****. In the real world, there are no differences....... Ryzolt is a BS meeeee tooooo drug that drives me insane.....
Well, I dance for quarters. I'm a ***** like that. And its a good second income.
Well, I mean, I guess I would take them if they were bounced my way.....
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Drug rep much?
And now that you mention the clinical trials, the data that you guys have been handing out would not push me towards using this. If you're going to use osteoarthritis for the set of CP patients, it would help if there is a decent difference between Nucynta and placebo.
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Tramadol is an excellent pain management medication... for dogs.
wow.
