Step I Understanding Coag Cascade

This forum made possible through the generous support of SDN members, donors, and sponsors. Thank you.
Get help with your application

Use all the free resources available to you from SDN: articles, guides, expert advising, forums discussions, and school research.

chromuffin

Full Member
7+ Year Member
Advertisement - Members don't see this ad
So I feel like Pathoma may be misdirecting/oversimplifying my understanding of the coag cascade. So I want some input from people learning coag cascade outside pathoma. Is the extrinsic coagulation pathway activated first in vivo? Then, Factor II/thrombin activates 5,8,11? Then Factor 11 activates 9, etc? And Factor 12 is merely used for PTT testing as a means of activating the intrinsic pathway without using the extrinsic pathway? This seems to make the most sense to me, but I'm not 100% sure.