urea and ecf

[cage92]

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whats is the effect of infusion of urea on ecf and icf and osmolarity?

 

[pd1112]

whats is the effect of infusion of urea on ecf and icf and osmolarity?

Depends on the osmolarity of the infusion. If isotonic, no change. If hypertonic, increased in both compartments.

 

[cage92]

urea in general in isotonic?

 

[pd1112]

What? Urea is a nitrogen compound. An infusion could have any concentration.
POsm = 2[Na] + [glucose]/18 + [BUN]/2.8
In general, urea has minimal effect on osmotic gradient because it freely distributes between ECF & ICF.

 

[cage92]

thank you so ecf and icf remain the same

 

[pd1112]

thank you so ecf and icf remain the same

Yes essentially, if the infusion is isotonic. If it were highly hypertonic, it might increase a little.

 

[aspiringmd1015]

what contributes to the omsolarity of any compartment are substances that are IMPERMEABLE to barriers, urea is freely permeable.

 

[cage92]

thanks man