UWorld question on pantothenate

[Pamplemousse123]

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Hi everyone,
In reference to uworld's Qid 1044 that asks which step requires pantothenate, I was wondering why can't the answer, "Glucose to ribose-5-P" be correct; the reaction from glucose -- ribulose 5 p --- ribose 5p requires transketolase, right? And transketolase requires B1, 2, 3, 5 and lipoic acid (B5 is pantothenate)...so why not?

Ans is OAA to citrate which reqires Acetyl coa.

Thanks in advance

 

[jjuva]

Hi everyone,
In reference to uworld's Qid 1044 that asks which step requires pantothenate, I was wondering why can't the answer, "Glucose to ribose-5-P" be correct; the reaction from glucose -- ribulose 5 p --- ribose 5p requires transketolase, right? And transketolase requires B1, 2, 3, 5 and lipoic acid (B5 is pantothenate)...so why not?

Ans is OAA to citrate which reqires Acetyl coa.

Thanks in advance

Transketolase requires just b1, not all of the others.

 

[Oreoomar]

The only complexes that require all 5 should be Pyruvate dehydrogenase, a-ketogluterate dehyrdrogenase, and branched chain amino acid dehydrogenase