Step I Uworld question - PAH concentration lowest

[voicesinmyhead]

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Uworld says PAH concentration is lowest at the bowmans capsule than anywhere else.

Wont the concentration at DCT be even lower?

 

[Distant]

PAH will Be Continuously Secreted Throughout the Tubules, So it's concentration will be the Lowest in the Point Where No Secretion has Yet Occurred.
IT IS NOT REABSORBED, so There is no way it's concentration will be lower moving Forward.

Due to Reabsorption of Na+,Cl- (In the Ascending Loop of Henle ) proximal to the DCT, (Where the Water is the most Dilute), PAH, However, will Be more concentrated than in the Bowman's Capsule .because it has been Secreted in the PCT.

 

[dyspareunia]

Uworld says PAH concentration is lowest at the bowmans capsule than anywhere else.

Wont the concentration at DCT be even lower?

PAH:
Freely filtered
Not reabsorbed
Secreted

You add more as you go along, plus there's less water at the beginning than at the end. More solute and less h20 = way more concentrated.