I did a deep dive and in general for 99214/ 99215, even for chemotherapy and Stage IV patients, this is how ASCO officially interprets the guidelines:
" Example: A moderate E/M code (99214) would be reported if: A patient presented with a new progression of bone metastasis while under treatment for breast cancer (moderate problems addressed). The physician reviewed the most recent CT scan (low level of data reviewed). It is determined the patient will have a change in chemotherapy due to the progression. (moderate/high level of risk dependent on the chemotherapy plan)."
I am not sure what the threshold is then for high risk of mortality or morbidity for a chemotherapy regimen or disease state. So, this opens a can worms whether metastatic pancreatic cancer on FOLFIRINOX is more high risk / higher therapeutic monitoring index than metastatic prostate cancer progressed on ADT on chemotherapy now. Both to me are 1) High risk conditions with high risk of morbidity / mortality. 2) Both chemotherapy regimens are high risk and carry therapeutic intense monitoring parameters. But reading ASCO's documents it would almost seem 992215 is only for ER / Hospitalization, which is also an improbable interpretation, as we would then equate a health maintenance visit for HTN/DM II and labs to treating someone with Carbo-Pem-Pem with metastatic NSCLC with multiple complications.