Good heavens, still etching dentin? Dr. Ray Bertollotti's newsletter has some brief reviews of Self-Etching Primers versus Total Etch:
http://www.adhesion.com/index.php?page=the_archive&akey=19
Here's a quote:
Van Meerbeek and colleagues currently state: "When bonding to enamel, an etch and rinse approach is definitely preferred, indicating that simple micro-mechanical interaction appears sufficient to achieve a durable bond to enamel. When bonding to dentin, a mild self-etch approach is superior, as it involves (like with glass-ionomers) additional ionic bonding with residual HAp. This additional primary chemical bonding definitely contributes to bond durability."
Definitely have a look at the SEM photos at the bottom of the page, and the commentary on the products they represent.
And:
http://www.adhesion.com/index.php?page=the_archive&akey=18
Speaks about Gluma a bit.
Truly, though, this article explains enamel and dentin bonding as well as any I've ever read, it's from an impartial and brilliant author, and the literature cited is impeccable:
http://www.dentistrytoday.com/materials/1483.html
(And looky where it was published, of all places! You just never know.)
There's more literature since 2003, of course. Yet to my knowledge no major practical developments have occurred since except the introduction of Danville Engineering's Prelude SE, which tweaked the chemistry of the already excellent Clearfil SE Bond.
Here's a suggested rubric:
If bonding largely to enamel or porcelain, Etch and bond. And Clearfil Photobond predictably gives among the highest bond strengths in the business. It also costs about 50 cents for a one-drop/one-drop application.
If bonding largely to dentin, which includes pretty much every posterior Class I and II and even V, Self-Etch! Please consider it strongly. Clearfil SE Bond and Danville Prelude SE give the highest consistent bond strengths, with Prelude SE having the advantages of lower film thickness, less transudation (though both are excellent on that score) and it does not stick to your metal sectional matrix bands. At all. Both also cost about 75 cents per one-drop application, though Prelude SE may be less.
We're talking consistent 32MPa bonds on dentin here, that hold up remarkably well over time.
I refer to cost because some systems overcharge and deliver lower, less consistent bond strengths. For example, the Prompt L-Pop system, while packaged cleverly, is $4.00 per application last time I checked, for far lower and less consistent dentin bond strengths than Prelude SE, and with transudation issues.
Did I mention no sensitivity? If used properly (and often if not) sensitivity with Self-Etch Primers is usually nil. I went through a brief but regrettable phase where I placed too thick of a first layer of flowable composite in a number of Class II preps. It shrank (not towards the light, that's a myth- towards the best bonded surface, which is the enamel walls of the proximal box). Later on we'd take our routine bitewings and I'd see a horrifying gap. For which I'd apologize to the patient for having to get them numb again and, of course, replace the restoration at no fee. Here's the thing though- even with 1mm+ gaps at the gingival margin,
no one was ever sensitive. It took a bitewing to find the problem.
By the way, as of 2010, to the best of my knowledge, compared to SE Bond and Prelude SE, every other Self-Etch product on the market had higher cost and greater transudation, which is probably what's driving the recommendations to use glass ionomer bases. I never use such bases and can never blame clinical failures, rare as they are, on Prelude SE or SE Bond. It's always me if something is flawed in a composite resin restoration. (Using an operating microscope for 6 months now, the issue of finding occasional gaps between the composite and the cavosurface has disappeared. Placing composite in a prep is now rather like spackling a wall. In the noonday sun at the beach. On #15. Distal.) Anyway I'd much rather bioengineer a hybrid layer over
all the dentin than place a non-adhesive base over much of it.
Apologies for riffing so far afield on your Gluma question, and it CAN be used under Self-Etching Primers. See Bertollotti's newsletter. Yet I felt compelled when I saw the rubric of Total Etch on dentin. The science on dentin bonding has regrettably not been disseminated widely enough though and I almost feel like saying:
"Friends don't let friends Total Etch dentin."
Read Pashley's article if you haven't by this point. You, and your patients, will not regret it.