When you are desperate for a propaganda win...

[Chartreuse Wombat]

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Changing the rules of the game before the game is up is generally frowned upon....

Government researchers changed metric to measure coronavirus drug remdesivir during clinical trial

 

[RickyScott]

The p for survival was 0.059- so 94% chance that there is an overall survival improvement?

 

[medgator]

Changing the rules of the game before the game is up is generally frowned upon....

Government researchers changed metric to measure coronavirus drug remdesivir during clinical trial

Guess that happens when there aren't many players?

 

[Lamount]

Changing the rules of the game before the game is up is generally frowned upon....

Government researchers changed metric to measure coronavirus drug remdesivir during clinical trial

Does it violate the scientific method? Yes.

If a loved one were admitted with Covid, would I want him/her to get remdesivir off study? Also yes

 

[Krukenberg]

The p for survival was 0.059- so 94% chance that there is an overall survival improvement?

can’t tell if this is a joke or not

 

[Chartreuse Wombat]

The p for survival was 0.059- so 94% chance that there is an overall survival improvement?

That is a common misinterpretation of a p-value.

p-values do not measure the probability that the studied hypothesis is true.

Ronald L. Wasserstein & Nicole A. Lazar (2016) The ASA Statement on p-Values: Context, Process, and Purpose, The American Statistician, 70:2, 129-133, DOI: 10.1080/00031305.2016.1154108

Principle 2

Have you seen the data?

 

[FrostyHammer]

If the vast majority of internal medicine docs can't design and interpret clinical trials properly, then why think anyone in pharma out government can? Just saying.

 

[scarbrtj]

The p for survival was 0.059- so 94% chance that there is an overall survival improvement?

It was discovered 50 years ago that Vitamin C injections improved survival in metastatic colon, lung, kidney, etc. cancer to the tune of p<0.0001.
Which is flat crazy that we aren't shooting up cancer patients with ascorbic acid today given the 99.99% chance it improves survival.
Must be conspiracy?

 

[medgator]

It was discovered 50 years ago that Vitamin C injections improved survival in metastatic colon, lung, kidney, etc. cancer to the tune of p<0.0001.
Which is flat crazy that we aren't shooting up cancer patients with ascorbic acid today given the 99.99% chance it improves survival.
Must be conspiracy?

Think i heard similar about a study of it in sepsis, but a recent one didn't corroborate that

 

[thecarbonionangle]

It was discovered 50 years ago that Vitamin C injections improved survival in metastatic colon, lung, kidney, etc. cancer to the tune of p<0.0001.
Which is flat crazy that we aren't shooting up cancer patients with ascorbic acid today given the 99.99% chance it improves survival.
Must be conspiracy?

i had a patient treat his cancer with vicks vaporub. He assured me he’d be fine. Maybe he is, maybe he isn’t. We’ll never Know!

 

[evilbooyaa]

I just want to see this data actually written up with as a paper, or even an abstract. How has it been a press release only for what seems like 3-5 days?

****, give a motivated Rad Onc resident or junior attending the data and a day, you'll get a full paper back.

FDA approvals based on a pharma-funded study that has not been reviewed in anyway and we're basing the data on a press release? Agree with the topic of the title on this one. Hope Fauci talking like trump ("game changer") is a one-off and his brain has not rotted due to his proximity to the administration.