I know it's not a good idea to base your entire decision on locale; however, I spent many of my undergrad. years regretting my college's location (Cleveland)...I know that Erie is very similar as far as weather/cleanliness goes. I would go with the one you felt most comfortable at during your visit.
I'm sorry I don't have any advice as far as either school's academic reputation. Good luck with whatever you decide.
I agree. Lewisburg is actually a charming little town in a really pretty area. I'm guessing it's not such a great place if you have a spouse who needs to find a job, though. WVSOM has pbl, so LECOM doesn't get an advantage there. LECOM is a lot cheaper, though. I'd still go to WVSOM.