Apologies if this is already addressed in one of the articles posted, but is anyone aware of studies of hormonal interventions in patients that are born female and effects on schizophrenia development/severity?
The thought occurs because of the higher rates of GDD in patients on the schizophrenia spectrum, and the protective effect of estrogen from schizophrenia. The potential clinical significance would be assessing for schizophrenia risk and including in discussion of risks/benefits with born-female patients before starting hormonal interventions, and whether increased monitoring for signs/symptoms of developing schizophrenia are warranted after starting intervention.
