There are several issues to consider. First if this is for a controlled substance it is invalid for two reasons. First the order has been changed and that is not permitted:
§1311.170 Transmission requirements.
(b) The electronic prescription application may print a prescription that has been transmitted only if an intermediary or the designated pharmacy notifies a practitioner that an electronic prescription was not successfully delivered to the designated pharmacy. If this occurs, the electronic prescription application may print the prescription for the practitioner's manual signature. The printed prescription must include information noting that the prescription was originally transmitted electronically to [name of the specific pharmacy] on [date/time] and that transmission failed.
(f) An electronic prescription must be transmitted from the practitioner to the pharmacy in its electronic form. At no time may an intermediary convert an electronic prescription to another form ( e.g., facsimile) for transmission.
Next if it is not completely electronic, computer to computer it will need a manual signature. If you get a fax for a Controlled substance with the an electronic signature you will need a verbal:
(d) A practitioner may sign a paper prescription in the same manner as he would sign a check or legal document (e.g., J.H. Smith or John H. Smith). Where an oral order is not permitted, paper prescriptions shall be written with ink or indelible pencil, typewriter, or printed on a computer printer and shall be manually signed by the practitioner. A computer-generated prescription that is printed out or faxed by the practitioner must be manually signed.
For non controlled Rxs you would have to consult your state law to see what they consider a valid signature.
You will never ever ever get in trouble with the board unless you are doing something illegal on a grand scale. They don't come in and start looking through your rxs for things.
My only (but not yet realized) worry is that 3rd party auditors will be instructed to look at these technical violations and use them as an excuse to deny payment.
Know your state law, use good judgement and document what you do and you will be fine,.