Another Cliffs bio Q

[Mstoothlady2012]

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Which of the following would be activated first in response to a body cell that has been invaded by viruses?

a) cytotoxic T cells
b) Natural killer cells
c) Antibodies
d) Macrophages
e) Neutrophils

What do you guys think? I so don't agree with cliffs answer... Thanks!

 

[Thundercatz]

I would pick A. All the others I think will be against bacterial infection.

 

[klutzy1987]

I was never great shakes at the immune system but i would say NK cells. dont jump on me if im wrong cuz i never did have the immune system down lol.

 

[wkawk2416]

i would pick e

 

[osimsDDS]

Which of the following would be activated first in response to a body cell that has been invaded by viruses?

a) cytotoxic T cells
b) Natural killer cells
c) Antibodies
d) Macrophages
e) Neutrophils

What do you guys think? I so don't agree with cliffs answer... Thanks!

hmm might be B...i think i would go with B

 

[topdent1]

Hmm..well, neutrophiles, macrophages, and natural killer cells are all in the second line of defense. I think the answer is antibodies because viruses are antigen specific and antibodies target specific antigens. All the other answers would be secreted but ultimately it would be up to the antibody to finish the virus. I have a feeling im wrong.

 

[osimsDDS]

actually if you really want to know what a great answer should be, it should be INTERFERONS...those take care of viruses that invade the body...

 

[klutzy1987]

I would pick A. All the others I think will be against bacterial infection.

Natural killer cells definitely attack virus infected cells so A is for sure wrong. I am pretty sure that it is NK cells.

 

[Thundercatz]

Yea, seem little tricky, but it stats that it being attack by virus. My instinct was also NK, but NK cells are in the humoral system with mainly is the line of defense against bacterial infections. Someone else please comment!

 

[Andrew324]

what page of cliffs is this on?

 

[osimsDDS]

Hmm..well, neutrophiles, macrophages, and natural killer cells are all in the second line of defense. I think the answer is antibodies because viruses are antigen specific and antibodies target specific antigens. All the other answers would be secreted but ultimately it would be up to the antibody to finish the virus. I have a feeling im wrong.

uhhmm macrophages are not the second line of defence, they are actually the first line of defence (non-specific), actually im pretty sure neutrophiles, macrophages, and NK cells are all non-specific

 

[Thundercatz]

Whats the answer in the Cliffs book?

 

[topdent1]

uhhmm macrophages are not the second line of defence, they are actually the first line of defence (non-specific), actually im pretty sure neutrophiles, macrophages, and NK cells are all
non-specific

They are the second line of defense. The second line of defense can be nonspecific too.

 

[Mstoothlady2012]

Lol...wow really fast responses. Hmm every1 has different opinion. Lol klutzy & osims I agree with you guys it should definitely be NK cells and I am 100% sure (took immuno just last semester) but cliffs says cytotoxic T cells. The question says first to be activated, which are definitely NK cells. Yea cytotoxic T cells does a better job at killing the viruses than NK but it takes them a while to respond (b/c they have to get activated and blah blah) , so till they come around NK cells take care of those virus cells. Uhh I am starting to hate cliffs a lil now.

 

[Mstoothlady2012]

I would pick A. All the others I think will be against bacterial infection.

NK work against viruses too and they have cytotoxic activity as well

 

[harrygt]

NK cells are responsible to attack virus infected and cancerous cells in the nonspecific cell defense. T cytotoxic do the same thing in the specific cell difense. I would pick "B", feel a bitter taste in my mouth, and move to the next question.
What Does that book say about the right answer?

 

[Mstoothlady2012]

i would pick e

Neutrophils doesnt have cytotoxic activity, so that doesnt work for viruses.

 

[topdent1]

I think SDN should open up a chat room for questions that require fast responses...its really inefficient sitting here refreshing your page every 30 seconds.

 

[Mstoothlady2012]

Hmm..well, neutrophiles, macrophages, and natural killer cells are all in the second line of defense. I think the answer is antibodies because viruses are antigen specific and antibodies target specific antigens. All the other answers would be secreted but ultimately it would be up to the antibody to finish the virus. I have a feeling im wrong.

these are first line of defense and they are non-specific, antibodies can't do nothing against viruses

 

[Mstoothlady2012]

Yea, seem little tricky, but it stats that it being attack by virus. My instinct was also NK, but NK cells are in the humoral system with mainly is the line of defense against bacterial infections. Someone else please comment!

NK cells are involved in innate immunity not humoral. Humoral immunity is mainly by B cells.

 

[Mstoothlady2012]

what page of cliffs is this on?

on pg 204 - # 18

 

[yakuza]

Hmm its either Natural killers or cytotoxic..

BUT since cytotoxic are specific killers, they'll straight up just target the virus while natural killers are non-specific and will also attack other things

 

[Thundercatz]

NK cells are involved in innate immunity not humoral. Humoral immunity is mainly by B cells.

Ok thanks for the clarification!

 

[Thundercatz]

Ok,

I think I got it!

I am reading EK and it states that humoral immunity is effective against bacteria, fungi, viruses, toxins, etc... but cell mediated is effective against infected cells.

The question states that a body cell is infected with a virus. What do you guys think? HEHE

 

[HoangDDS]

Which of the following would be activated first in response to a body cell that has been invaded by viruses?

a) cytotoxic T cells
b) Natural killer cells
c) Antibodies
d) Macrophages
e) Neutrophils

What do you guys think? I so don't agree with cliffs answer... Thanks!

It asked for specifically activated. Therefore it has to be Tc cells. NK cells might detect the virus infected cell first, but they dont require activation.

 

[Mstoothlady2012]

Ok,

I think I got it!

I am reading EK and it states that humoral immunity is effective against bacteria, fungi, viruses, toxins, etc... but cell mediated is effective against infected cells.

The question states that a body cell is infected with a virus. What do you guys think? HEHE

once again NK cells are special cells. They are not in humoral neither in cell-mediated. They work under innate system and they have cytotoxic activity. So yes when they see infected cell they can kill it.

 

[Mstoothlady2012]

It asked for specifically activated. Therefore it has to be Tc cells. NK cells might detect the virus infected cell first, but they dont require activation.

oh yea that's true!! NK cells don't have to be activated. Ok then the answer should be Tc cells. But if the question were to ask which comes first then it would be NK cells. One word messed up the whole question lol

 

[1800RAW]

It asked for specifically activated. Therefore it has to be Tc cells. NK cells might detect the virus infected cell first, but they dont require activation.

bump, having the same question

can anyone else confirm this? I also thought the answer was NK cells but I suppose this guy is correct in saying they dont require activation, which makes this question really lame.

thoughts?

 

[Neil45]

.

 

[rmm30]

NK cells are the first lymphocytes to attack virally infected cells (and tumor cells). They are part of the innate immune resposes (that kicks in just hours after infection). They are activated by cytokine release of infected cells. Whether or not they can lyse a virus infected cell w.out being activated, i dont know. because the immune system is exceedingly complex and interconnected, there is very little that can be said that is black and white. Considering the level of detail in cliffs, i would say that the answer is b. please dont quote me tho.

 

[1800RAW]

NK cells are the first lymphocytes to attack virally infected cells (and tumor cells). They are part of the innate immune resposes (that kicks in just hours after infection). They are activated by cytokine release of infected cells. Whether or not they can lyse a virus infected cell w.out being activated, i dont know. because the immune system is exceedingly complex and interconnected, there is very little that can be said that is black and white. Considering the level of detail in cliffs, i would say that the answer is b. please dont quote me tho.

yup, exactly my logic. NK cells do have cytotoxic activity and as a part of the innate, nonspecific immune system would be quickly active once a pathogen was encountered.

however, cliffs says that the answer is A, and that the specific immune system would first be activated, followed by the nonspecific immune response, which doesnt make sense