LIke many have said, why medicine and what your prior experience would make you a competitive physician is the key.
As you may already know, medical school application numbers dropped during tech bubble, then when it burst, applicant numbers have been rising fast. In fact it is becoming more competitive than ever. e.g. at GUSOM, the class of 2010 had the highest av GPA and MCAT scores they ever had, also the lowest acceptance percentage. I am sure the trend is similar nationwide.
I am sure there is a reason why you are pursuing medicine after working in IT for many years. If that reason is something that is not going to be welcomed by ADCOM, then I would think hard about going to medicine.
I am going to put my flame jacket on, but so many got into IT for the potential of making quick bucks and sometimes quite a lot of bucks. Now that job market is not as hot, many are looking into other profession. ADCOMS know this and the last thing they want is someone pursuing medicine because of job security and $$$$.
Think about this. If IT and high tech boom comes back, and with your experience, you have the potential to earn big bucks and retire in 10-15 years with stock option, etc. would you stick with IT or would you still pursue medicine?