From the study I provided a link to previously:
Interestingly, while the majority of patients in the ISB group reported axillary pain at 6 hours (71%), it was not present in every patient. There could be several possible explanations for this finding. First, it is conceivable that in some patients, the ISB was performed more caudal than intended and therefore blockade of the lower trunk of the brachial plexus was achieved. This could explain the lack of axillary pain given that the medial brachial cutaneous nerve and the medial pectoral nerve both originate from the lower trunk of the brachial plexus. Interestingly, a prior study investigating whether an ISB performed at the lowest bra- chial plexus nerve roots could adequately block the hand and forearm revealed a success rate of 6%–33%.11 Second, it is possible that because of anatomic variability, the location of the incision for the open biceps tenodesis was actually in an area of the arm innervated by the axillary nerve, which would theoretically be covered by an ISB.