I agree with other posters here who have said that it's important to read about things outside of medicine. Most of my interviewers asked me about topics outside of medicine (I'm assuming to see if I had a life), and one specifically asked me what the most recent, non-medical/science book I had read was.
Just know what's going on in the world. I was interviewing during the great Writer's Strike of 07 🙂laugh🙂, and in one interview, I spent 20 minutes out of a 30 minute interview talking about its effect on SNL, SNL's current writing staff and its politics, what years SNL was better, and whether or not SNL would come back stronger because of the strike. It was weird but cool at the same time.
In another, I talked to the dean of a med school for 10 minutes about Quentin Tarantino and Pulp Fiction. Turns out it was his wife's favorite movie (mine as well), and we were debating its merits.
All in all, just figure out what you're interested in outside of science/medicine and be able to talk about it. It makes the interview that much more fun and relaxing when you can talk about real stuff.