Bio Questions...need help

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lovechild404

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  1. Dental Student
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1) In designing antibiotics to treat infections caused by faculative anaerobes in humans, the target which would be most attractive are inhibitors of bacterial:
a. mRNA splicing
b. electron transport
c. poly-A addition for mRNAs
d. transcription
e. none of the above

2) When measuring reaction velocity as a function of substrate concentration, a researcher usually keeps the concentration of enzyme at a constant level. WHat would happen if the enzyme concentration were NOT kept constant?
a. Vmax would stay constant, but V would change
b. Vmax would stay constant, but Km would change
c. Vmax would change, but Km would remain constant
d. Both Vmax and Km would change
e. none of the above would necessarily occur

3) Which of the following sensory receptors are Not mecanoreceptors?
a. aortic baroreceptor
b. hearing receptors in the Organ of Corti
c. rods and cones
d. pacinian corpuscles
e. golgi tendon organs

4) A competitive inhibitor causes:
a. Vmax to decrease and Km to stay unchanged
b. Vmax to stay unchanged and Km to decrease
c. Vmax to stay unchanged and Km to increase
d. Vmax to increase and Km to remain unchanged
e. neither Vmax or Km will be affected.

5) Is prokaryotic mRNA monocistronic?
a. true
b. false

6) Including the ATP used for amino acid activation/tRNA loading, approximately how many ATP equivalents are required to synthesize a 200 amino acid protein?
a. 200
b. 400
c. 600
d. 800
e. 1000
 
1. In designing antibiotics to treat infections caused by faculative anaerobes in humans, the target which would be most attractive are inhibitors of bacterial:
a. mRNA splicing
b. electron transport
c. poly-A addition for mRNAs
d. transcription
e. none of the above

2. When measuring reaction velocity as a function of substrate concentration, a researcher usually keeps the concentration of enzyme at a constant level. WHat would happen if the enzyme concentration were NOT kept constant?
a. Vmax would stay constant, but V would change
b. Vmax would stay constant, but Km would change
c. Vmax would change, but Km would remain constant
d. Both Vmax and Km would change
e. none of the above would necessarily occur

3) Which of the following sensory receptors are Not mecanoreceptors?
a. aortic baroreceptor
b. hearing receptors in the Organ of Corti
c. rods and cones
d. pacinian corpuscles
e. golgi tendon organs

4) A competitive inhibitor causes:
a. Vmax to decrease and Km to stay unchanged
b. Vmax to stay unchanged and Km to decrease
c. Vmax to stay unchanged and Km to increase
d. Vmax to increase and Km to remain unchanged
e. neither Vmax or Km will be affected.

5) Is prokaryotic mRNA monocistronic?
a. true
b. false

6) Including the ATP used for amino acide activation/tRNA loading, approximately how many ATP equivalents are required to synthesize a 200 amino acide protein?
a. 200
b. 400
c. 600
d. 800
e. 1000

Prokaryotic mRNA is monocistronic. And I think competitive inhibitors increase Km without changing Vmax.
 
this probably isn't much help, but based on my DAT, these questions are a lot more difficult than any question I had...I really doubt you'll be asked anything along these lines...it is good to be prepared though (sorry I dont know any of the answers off the top of my head)
 
For #3: Mechanoreceptors are sensory receptors:
b: sensory (ear)
c: sensory (eye)
d: sensory (skin)
e: sensory (brain)

So I think choice "a" is not a mechanoreceptor.

For #4: I found the following passage from wikipedia- I'm confused though, is Km increased or decreased?

In this case, the maximum speed of the reaction is unchanged, while the apparent affinity of the substrate to the binding site is decreased (it means: the Kd dissociation constant is apparently increased). The change in Km (Michaelis-Menten constant) is parallel to the alteration in Kd. Any given competitive inhibitor concentration can be overcome by increasing the substrate concentration in which case the substrate will outcompete the inhibitor in binding to the enzyme.



do you have the answers for these, please?
I would love to know the answers!!!!
 
love.. where are you getting these questions from? I have not seen any of those in my review books.
 
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