biochem clarification on FA

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DR Kufi

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hello can someone please help me understand what is meant by the +'s and -'s next to all the ATP, AMP, citrate etc. in page 95 of 2008 FA under "glycolysis regulation and key enzyme." I realize this is probably something stupid that I could've figured out by myself but sort of freaking out trying to get through everything and don't wanna be stuck on this

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sorry everyone,
i figured it out. All it is indicating is whether it activates or deactivates each step....duh...my BAD
 
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