No, you just have to pass the NAPLEX and CPJE, both of which are easy to pass.
That being said, the CA Board of Pharmacy is the slowest and least transparent organization I have ever had to work with in my 28 years on this planet.
Just a heads up, it took them 3 months to process my application and give me authorization to take the CPJE and NAPLEX. Luckily, I scheduled my NAPLEX through NC, where I attended school and was authorized immediately.
Also, CA requires the CPJE for whatever reason, it's easier than the NAPLEX, though 50% of out-of-state students fail it. They do a quality assurance review on the exam twice a year to ensure fairness between exams. If you schedule your exam within their QA period, they potentially won't give you your results for months.
It's a long process to say the least. Also, after you pass both exams you have to send them a check for $150 and wait 10 business days for them to post your license.
Not more difficult in the sense that you are not adequately trained to pass the CPJE, but more difficult in the sense that the CA Board of Pharmacy sucks for a multitude of reasons.