- Joined
- Dec 28, 2015
- Messages
- 10
- Reaction score
- 4
I have been getting myself confused about diastolic versus systolic blood pressures.
Alpha-1 agonists cause smooth muscle contraction and increase vasoconstriction, which increases diastolic blood pressure; meanwhile, beta-1 agonists increase chronotropy + ionotrophy, which increases the systolic BP. However, as age increases, there is a decrease in arterial compliance and this increases systolic blood pressure leading to a widened pulse pressure.
Am I understanding this correctly? And if so, can someone please explain how decrease compliance of a vessel and vasoconstriction are different and affect systolic and diastolic BPs respectively?
Thanks in advance!
Alpha-1 agonists cause smooth muscle contraction and increase vasoconstriction, which increases diastolic blood pressure; meanwhile, beta-1 agonists increase chronotropy + ionotrophy, which increases the systolic BP. However, as age increases, there is a decrease in arterial compliance and this increases systolic blood pressure leading to a widened pulse pressure.
Am I understanding this correctly? And if so, can someone please explain how decrease compliance of a vessel and vasoconstriction are different and affect systolic and diastolic BPs respectively?
Thanks in advance!