Agree with the above that it depends somewhat on your goals, but I'll generalize a bit (and I can only generalize because we don't have too many details here, like your goals, pros/cons of the schools in your eyes, etc).
If sizable is >100k I'd take it in a heartbeat - few things are worth such a lump sum of money, and if it means you have to search a little harder for certain opportunities at Temple I'd do it for that money. If it's less than that but more than ~60ish over 4 years, I think you need to imagine where you want to be (aka do you care about research as much, are you potentially interested in a more competitive specialty, etc) and choose accordingly - essentially, if Case's strengths don't offer that much, then don't pay for them. Less than 50k I'd say it's definitely nice but Cleveland is going to have lower cost of living and the benefits probably are worth more.