I am aware of case reports of epidural hematoma after TFESI. That one seems like a gray area
Exceptionally rare, and you know what is not rare?
Embolic events after stopping Coumadin.
Edit - Speaking of Coumadin. Y'all know how finicky it is to get a pt to Tx INR and keep them there right? I read a study years ago claiming 60% of the time a pt on Coumadin is Tx, and 40% they're either over/under.
So maybe 6 weeks ago (maybe longer...wtf knows these days), I sent a frail woman to the ED with dexamethasone 10mg via lumbar TFESI.
She was on Xarelto or Eliquis maybe...One of the newer agents and not Coumadin.
We've all had plenty of pts get dexamethasone and have that 48 hr hypomanic, can't sleep, anxious stuff. She had CP and SOB - That dexamethasone sped her up and her A fib went nuts.
Now had she stopped that thinner, what happens?
If you stop it, you restart it that night after the shot...But had she been on Coumadin, she wouldn't have Tx yet and who knows what would have happened there...CVA?
So don't stop the thinner for TFESI, especially not a lower lumbar TFESI.